Prognostic significance of minimal residual disease in. Outcome of relapsed infant acute lymphoblastic leukemia. A treatment protocol for infants younger than 1 year. Outcome of congenital acute lymphoblastic leukemia treated on the interfant99 protocol. Request pdf a treatment protocol for infants younger than 1 year with acute lymphoblastic leukaemia interfant99. Pdf outcome of relapsed infant acute lymphoblastic leukemia. Outcome of relapsed infant acute lymphoblastic leukemia treated on the interfant99 protocol article pdf available in blood 11418. The present study reports the outcome of 30 patients with congenital all treated with the uniform interfant99 protocol, a hybrid regimen combining all. These 99 patients were all blineage all with no significant differences in. Between may 1999 and january 2006, researchers in 22 countries enrolled 376 patients aged 1 year or younger with previously untreated all into. A treatment protocol for infants younger than 1 year with acute lymphoblastic leukaemia interfant 99. Pdf outcome of congenital acute lymphoblastic leukemia. Clinical trials and observations outcome of congenital acute lymphoblastic leukemia treated on the interfant99 protocol marieke h.
Outcome of congenital acute lymphoblastic leukemia treated on the interfant 99 protocol. An observational study and a multicentre randomised trial. Outcome of congenital acute lymphoblastic leukemia treated. The interfant99 protocol was the first treatment protocol of this collaborative group that consisted of all major european study groups and several. Outcome of infant all in interfant99 study and other published studies. Prognostic significance of minimal residual disease in infants with. A treatment protocol for infants younger than 1 year with acute lymphoblastic leukaemia interfant99. The interfant99 treatment was a hybrid regimen combining standard all treatment with. The interfant 06 treatment protocol compares the efficacy of two intensification chemotherapy schedules, which are administered earlier than those used in our interfant 99 study ie, immediately after the induction therapy. Vol 370 july 21, 2007 a treatment protocol for infants younger than 1 year with acute lymphoblastic leukaemia interfant99.
Infant acute lymphoblastic leukemia semantic scholar. Institutes participating in study groups of interfant99 pdf, 32. The interfant 99 trial design, the inclusion criteria, and recruitment methods have been published earlier. Outcome of infants younger than 1 year with acute lymphoblastic. Outcome of congenital acute lymphoblastic leukemia treated on the. Outcome of relapsed infant acute lymphoblastic leukemia treated on the interfant99 protocol skip to main content thank you for visiting. A treatment protocol for infants younger than 1 year with. Outcome of relapsed infant acute lymphoblastic leukemia treated on the interfant 99 protocol skip to main content thank you for visiting.
Patients in the interfant 06 study are now being stratified according to the prognostic factors identified in our study. Out of the 478 patients enrolled in the interfant99 protocol, 99 patients were included in the mrd study. Outcome of relapsed infant acute lymphoblastic leukemia treated on the interfant 99 protocol article pdf available in blood 11418. Outcome of relapsed infant acute lymphoblastic leukemia treated on the interfant99 protocol. Of the 518 infants diagnosed with all, which account for approximately 3% of the all population, 35 patients. A late intensification course vimaram improves the outcome of infants with acute lymphoblastic. Vol 370 july 21, 2007 a treatment protocol for infants younger than 1 year with acute lymphoblastic leukaemia interfant 99. International collaborative treatment protocol for infants. Pdf outcome of relapsed infant acute lymphoblastic. Because interfant99 showed outcome differences between the west.
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